Over the past eight years, I had the opportunity to work closely with prestigious institutions across Europe, including the Karolinska Institute in Sweden, Charité Medical University in Berlin, Germany, ETH Zurich in Switzerland, University Hospital Zurich, and the Hasso Plattner Institute in Germany. In addition to these academic engagements, I also interned with leading pharmaceutical company AstraZeneca. Currently, I am engaged in a diagnostic biotech company, where I serve as a bioinformatics data scientist operating within the pharmaceutical domain.
The tumor profiler project, which was carried out at ETH Zurich and generously funded by Roche. As part of the team, I actively contributed to the development of the pipeline specifically designed for RNA-seq and single-cell data analysis, encompassing the entire workflow from processing raw fastq files to calculating hypoxia scores. This involved implementing robust methodologies and incorporating cutting-edge techniques to ensure accurate and comprehensive results.
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia
The other projects, I have actively contributed, RIP-seq data analysis on breast cancer, DNA-seq, RNA-seq, and proteomics data analysis on leukemia patients.
The pipeline fetches data from the database, and performs statistical significance of the variants between the control and disease cohorts. Fischer's exact test is used for the analysis.